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Trypsin Cleavage Stabilizes the Rotavirus VP4 Spike

Trypsin enhances rotavirus infectivity by an unknown mechanism. To examine the structural basis of trypsin-enhanced infectivity in rotaviruses, SA11 4F triple-layered particles (TLPs) grown in the absence (nontrypsinized rotavirus [NTR]) or presence (trypsinized rotavirus [TR]) of trypsin were chara...

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Bibliografiset tiedot
Päätekijät: Crawford, Sue E., Mukherjee, Sharmila K., Estes, Mary K., Lawton, Jeffery A., Shaw, Andrea L., Ramig, Robert F., Prasad, B. V. Venkataram
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC114321/
https://ncbi.nlm.nih.gov/pubmed/11390607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6052-6061.2001
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