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Markedly Increased Susceptibility to Natural Sheep Scrapie of Transgenic Mice Expressing Ovine PrP

The susceptibility of sheep to scrapie is known to involve, as a major determinant, the nature of the prion protein (PrP) allele, with the VRQ allele conferring the highest susceptibility to the disease. Transgenic mice expressing in their brains three different ovine PrP(VRQ)-encoding transgenes un...

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Kaydedildi:
Yayımlandı:J Virol
Asıl Yazarlar: Vilotte, Jean-Luc, Soulier, Solange, Essalmani, Rachid, Stinnakre, Marie-George, Vaiman, Daniel, Lepourry, Laurence, Da Silva, Jose Costa, Besnard, Nathalie, Dawson, Mike, Buschmann, Anne, Groschup, Martin, Petit, Stephanie, Madelaine, Marie-Francoise, Rakatobe, Sabine, Le Dur, Annick, Vilette, Didier, Laude, Hubert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2001
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114313/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.5977-5984.2001
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