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Marked influence of the route of infection on prion strain apparent phenotype in a scrapie transgenic mouse model

Prion strains yield specific neuropathological features including spongiform degeneration and deposition patterns of pathological prion protein. Their invariant regional distribution, following variations in the infection route, has led to the proposal that prions replicate preferentially in defined...

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Detalles Bibliográficos
Principais autores: Christelle Langevin, Olivier Andréoletti, Annick Le Dur, Hubert Laude, Vincent Béringue
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2011-01-01
Series:Neurobiology of Disease
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0969996110003116
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