Markedly Increased Susceptibility to Natural Sheep Scrapie of Transgenic Mice Expressing Ovine PrP

The susceptibility of sheep to scrapie is known to involve, as a major determinant, the nature of the prion protein (PrP) allele, with the VRQ allele conferring the highest susceptibility to the disease. Transgenic mice expressing in their brains three different ovine PrP(VRQ)-encoding transgenes un...

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Библиографические подробности
Главные авторы: Vilotte, Jean-Luc, Soulier, Solange, Essalmani, Rachid, Stinnakre, Marie-George, Vaiman, Daniel, Lepourry, Laurence, Da Silva, Jose Costa, Besnard, Nathalie, Dawson, Mike, Buschmann, Anne, Groschup, Martin, Petit, Stephanie, Madelaine, Marie-Francoise, Rakatobe, Sabine, Le Dur, Annick, Vilette, Didier, Laude, Hubert
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC114313/
https://ncbi.nlm.nih.gov/pubmed/11390599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5977-5984.2001
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