G(1)/S Cell Cycle Arrest Provides Anoikis Resistance through Erk-Mediated Bim Suppression

Proper attachment to the extracellular matrix is essential for cell survival. Detachment from the extracellular matrix results in an apoptotic process termed anoikis. Anoikis induction in MCF-10A mammary epithelial cells is due not only to loss of survival signals following integrin disengagement, b...

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Main Authors: Collins, Nicole L., Reginato, Maurico J., Paulus, Jessica K., Sgroi, Dennis C., LaBaer, Joshua, Brugge, Joan S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
主題:
Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140593/
https://ncbi.nlm.nih.gov/pubmed/15923641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5282-5291.2005
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