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Hypoxia Suppression of Bim and Bmf Blocks Anoikis and Luminal Clearing during Mammary Morphogenesis

Proper adhesion to extracellular matrix is critical for epithelial cell survival. Detachment from matrix signals results in apoptosis, referred to as anoikis. Selective apoptosis of cells that become detached from matrix is associated with the formation of a lumen in three-dimensional mammary epithe...

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Detalhes bibliográficos
Main Authors: Whelan, Kelly A., Caldwell, Sarah A., Shahriari, Kristina S., Jackson, S. RaElle, Franchetti, Lisa D., Johannes, Gregg J., Reginato, Mauricio J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982135/
https://ncbi.nlm.nih.gov/pubmed/20861305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-04-0353
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