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Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

The formation of a lumen in three-dimensional mammary epithelial acinar structures in vitro involves selective apoptosis of centrally localized cells that lack matrix attachment. Similarly, apoptosis is induced by forced detachment of mammary epithelial cells from matrix, a process referred to as an...

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Detalhes bibliográficos
Main Authors: Schmelzle, Tobias, Mailleux, Arnaud A., Overholtzer, Michael, Carroll, Jason S., Solimini, Nicole L., Lightcap, Eric S., Veiby, Ole P., Brugge, Joan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820662/
https://ncbi.nlm.nih.gov/pubmed/17360431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700115104
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