Induction of DNA Damage Signaling upon Rift Valley Fever Virus Infection Results in Cell Cycle Arrest and Increased Viral Replication

Rift Valley fever virus (RVFV) is a highly pathogenic arthropod-borne virus infecting a wide range of vertebrate hosts. Of particular interest is the nonstructural NSs protein, which forms large filamentous fibril bundles in the nucleus. Past studies have shown NSs to be a multifaceted protein impor...

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Main Authors: Baer, Alan, Austin, Dana, Narayanan, Aarthi, Popova, Taissia, Kainulainen, Markus, Bailey, Charles, Kashanchi, Fatah, Weber, Friedemann, Kehn-Hall, Kylene
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293538/
https://ncbi.nlm.nih.gov/pubmed/22223653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296608
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