Bim Regulation of Lumen Formation in Cultured Mammary Epithelial Acini Is Targeted by Oncogenes

Epithelial cells organize into cyst-like structures that contain a spherical monolayer of cells that enclose a central lumen. Using a three-dimensional basement membrane culture model in which mammary epithelial cells form hollow, acinus-like structures, we previously demonstrated that lumen formati...

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Autors principals: Reginato, Mauricio J., Mills, Kenna R., Becker, Esther B. E., Lynch, Danielle K., Bonni, Azad, Muthuswamy, Senthil K., Brugge, Joan S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140636/
https://ncbi.nlm.nih.gov/pubmed/15899862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4591-4601.2005
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