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Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly

Our understanding of the mechanisms by which ducts and lobules develop is derived from model organisms and three-dimensional (3D) cell culture models wherein mammalian epithelial cells undergo morphogenesis to form multicellular spheres with a hollow central lumen. However, the mechanophysical prope...

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Autors principals: Wang, Hui, Lacoche, Sam, Huang, Ling, Xue, Bin, Muthuswamy, Senthil K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538193/
https://ncbi.nlm.nih.gov/pubmed/23248267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201141110
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