Unfractionated heparin inhibits thrombin-catalysed amplification reactions of coagulation more efficiently than those catalysed by factor Xa.

We have proposed previously that the steps in coagulation most sensitive to inhibition by heparin are the thrombin-dependent amplification reactions, and that prothrombinase is formed in heparinized plasma only after Factor Xa activates Factor VIII and Factor V. These propositions were based on the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ofosu, F A, Hirsh, J, Esmon, C T, Modi, G J, Smith, L M, Anvari, N, Buchanan, M R, Fenton, J W, Blajchman, M A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1989
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135548/
https://ncbi.nlm.nih.gov/pubmed/2920007
Tagiau: Ychwanegu Tag
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