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Vif is an auxiliary factor of the HIV-1 reverse transcriptase and facilitates abasic site bypass
The HIV-1 accessory protein Vif was found to modulate the RNA- and DNA-dependent DNA synthesis activity of the viral RT (reverse transcriptase) in two ways: (i) it stimulated the binding of the viral RT to the primer by increasing the association rate k(cat)/K(m) and by decreasing the thermodynamic...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Portland Press Ltd.
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133740/ https://ncbi.nlm.nih.gov/pubmed/15315477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040914 |
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