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Vif is an auxiliary factor of the HIV-1 reverse transcriptase and facilitates abasic site bypass

The HIV-1 accessory protein Vif was found to modulate the RNA- and DNA-dependent DNA synthesis activity of the viral RT (reverse transcriptase) in two ways: (i) it stimulated the binding of the viral RT to the primer by increasing the association rate k(cat)/K(m) and by decreasing the thermodynamic...

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Bibliografske podrobnosti
Main Authors: Cancio, Reynel, Spadari, Silvio, Maga, Giovanni
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133740/
https://ncbi.nlm.nih.gov/pubmed/15315477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040914
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