Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase

The HIV-1 accessory protein Vif plays a dual role: it counteracts the natural restriction factors APOBEC3G and 3F and ensures efficient retrotranscription of the HIV-1 RNA genome. We have previously shown that Vif can act as an auxiliary factor for HIV-1 reverse transcriptase (RT), increasing its ra...

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Autori principali: Kataropoulou, Alexandra, Bovolenta, Chiara, Belfiore, Amalia, Trabatti, Sonia, Garbelli, Anna, Porcellini, Simona, Lupo, Rossella, Maga, Giovanni
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699511/
https://ncbi.nlm.nih.gov/pubmed/19369217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp226
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