Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

A series of 3-3-{2-[2-3-methyl-4-phenyl-2,3-dihydro-1,3-thiazol-2-ylidene]hydrazin-1-ylidene-2,3-dihydro-1H-indol-2-one derivatives has been designed and synthesized to study their activity on both HIV-1 (Human Immunodeficiency Virus type 1) RT (Reverse Transcriptase) associated functions. These der...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Meleddu, Rita, Distinto, Simona, Corona, Angela, Tramontano, Enzo, Bianco, Giulia, Melis, Claudia, Cottiglia, Filippo, Maccioni, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010014/
https://ncbi.nlm.nih.gov/pubmed/27766892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1238366
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