Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids

[Image: see text] A series of isatin–dihydropyrazole hybrids have been synthesized in order to assess their potential as anticancer agents. In particular, 12 compounds were evaluated for their antiproliferative activity toward A549, IGR39, U87, MDA-MB-231, MCF-7, BT474, BxPC-3, SKOV-3, and H1299 cel...

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發表在:ACS Med Chem Lett
Main Authors: Meleddu, Rita, Petrikaite, Vilma, Distinto, Simona, Arridu, Antonella, Angius, Rossella, Serusi, Lorenzo, Škarnulytė, Laura, Endriulaitytė, Ugnė, Paškevičiu̅tė, Miglė, Cottiglia, Filippo, Gaspari, Marco, Taverna, Domenico, Deplano, Serenella, Fois, Benedetta, Maccioni, Elias
格式: Artigo
語言:Inglês
出版: American Chemical Society 2018
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466827/
https://ncbi.nlm.nih.gov/pubmed/30996798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00596
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