Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids

[Image: see text] A series of isatin–dihydropyrazole hybrids have been synthesized in order to assess their potential as anticancer agents. In particular, 12 compounds were evaluated for their antiproliferative activity toward A549, IGR39, U87, MDA-MB-231, MCF-7, BT474, BxPC-3, SKOV-3, and H1299 cel...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Meleddu, Rita, Petrikaite, Vilma, Distinto, Simona, Arridu, Antonella, Angius, Rossella, Serusi, Lorenzo, Škarnulytė, Laura, Endriulaitytė, Ugnė, Paškevičiu̅tė, Miglė, Cottiglia, Filippo, Gaspari, Marco, Taverna, Domenico, Deplano, Serenella, Fois, Benedetta, Maccioni, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466827/
https://ncbi.nlm.nih.gov/pubmed/30996798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00596
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