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Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

In all of eight tested human cells and cell lines with inducible indoleamine 2,3-dioxygenase (EC 1.13.11.17) tetrahydrobiopterin biosynthesis was activated by interferon-gamma. This was demonstrated by GTP cyclohydrolase I (EC 3.5.4.16) activities and intracellular neopterin and biopterin concentrat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Werner, E R, Werner-Felmayer, G, Fuchs, D, Hausen, A, Reibnegger, G, Wachter, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133353/
https://ncbi.nlm.nih.gov/pubmed/2511835
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