Interferon gamma-resistant mutants are defective in the induction of indoleamine 2,3-dioxygenase.
Several mutants of the human cell line ME-180 resistant to the cytotoxic effect of interferon gamma (IFN-gamma) were isolated after mutagenesis with nitrosoguanidine. Two of the mutant lines (ME-IR3b and ME-IR6g) examined had significantly lower induction levels of the L-tryptophan (L-Trp) degradati...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2506547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7144 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|