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Interferon gamma-resistant mutants are defective in the induction of indoleamine 2,3-dioxygenase.

Several mutants of the human cell line ME-180 resistant to the cytotoxic effect of interferon gamma (IFN-gamma) were isolated after mutagenesis with nitrosoguanidine. Two of the mutant lines (ME-IR3b and ME-IR6g) examined had significantly lower induction levels of the L-tryptophan (L-Trp) degradati...

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Sonraí Bibleagrafaíochta
Main Authors: Feng, G S, Taylor, M W
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1989
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC298012/
https://ncbi.nlm.nih.gov/pubmed/2506547
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