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Substrate and cofactor requirements of indoleamine 2,3-dioxygenase in interferon-gamma treated cells: Utilization of oxygen rather than superoxide
Much attention has been paid in initial biochemical studies on the ability of indoleamine 2,3-dioxygenase to use superoxide as substrate to cleave tryptophan to N-formyl kynurenine. This ability, however, is limited to the ferric form of the enzyme only, whereas the ferrous form requires oxygen rath...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851152/ https://ncbi.nlm.nih.gov/pubmed/17430107 |
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