Detection of bacterial pyrogens on the basis of their effects on gamma interferon-mediated formation of neopterin or nitrite in cultured monocyte cell lines.

In a number of mammalian cell types, pteridine biosynthesis from guanosine 5'-triphosphate and formation of nitric oxide from L-arginine are induced by gamma interferon (IFN-gamma) and bacterial lipopolysaccharide (LPS). We assessed the possibility of using such metabolic alterations for the in vitr...

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Detalhes bibliográficos

Publicado no:	Clin Diagn Lab Immunol
Principais autores:	Werner-Felmayer, G, Baier-Bitterlich, G, Fuchs, D, Hausen, A, Murr, C, Reibnegger, G, Werner, E R, Wachter, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7664177/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.2.3.307-313.1995
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