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Detection of bacterial pyrogens on the basis of their effects on gamma interferon-mediated formation of neopterin or nitrite in cultured monocyte cell lines.

In a number of mammalian cell types, pteridine biosynthesis from guanosine 5'-triphosphate and formation of nitric oxide from L-arginine are induced by gamma interferon (IFN-gamma) and bacterial lipopolysaccharide (LPS). We assessed the possibility of using such metabolic alterations for the in...

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Autors principals: Werner-Felmayer, G, Baier-Bitterlich, G, Fuchs, D, Hausen, A, Murr, C, Reibnegger, G, Werner, E R, Wachter, H
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC170151/
https://ncbi.nlm.nih.gov/pubmed/7664177
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