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Scrapie Pathogenesis in Subclinically Infected B-Cell-Deficient Mice

Prion infections can present without clinical manifestations. B-cell deficiency may be a model for subclinical transmissible spongiform encephalopathy, since it protects mice from disease upon intraperitoneal administration of scrapie prions; however, a proportion of B-cell-deficient mice accumulate...

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Bibliografiske detaljer
Main Authors: Frigg, Rico, Klein, Michael A., Hegyi, Ivan, Zinkernagel, Rolf M., Aguzzi, Adriano
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112993/
https://ncbi.nlm.nih.gov/pubmed/10516067
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