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Alteration of B-Cell Subsets Enhances Neuroinvasion in Mouse Scrapie Infection

Acquired forms of prion diseases or transmissible spongiform encephalopathies are believed to occur following peripheral exposure. Prions initially accumulate in the lymphoid system before spreading to the nervous system, but the underlying mechanisms for prion transfer between the two systems are s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: von Poser-Klein, Christine, Flechsig, Eckhard, Hoffmann, Tanja, Schwarz, Petra, Harms, Harry, Bujdoso, Raymond, Aguzzi, Adriano, Klein, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268467/
https://ncbi.nlm.nih.gov/pubmed/18199638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02036-07
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