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Alteration of B-Cell Subsets Enhances Neuroinvasion in Mouse Scrapie Infection

Acquired forms of prion diseases or transmissible spongiform encephalopathies are believed to occur following peripheral exposure. Prions initially accumulate in the lymphoid system before spreading to the nervous system, but the underlying mechanisms for prion transfer between the two systems are s...

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Autors principals: von Poser-Klein, Christine, Flechsig, Eckhard, Hoffmann, Tanja, Schwarz, Petra, Harms, Harry, Bujdoso, Raymond, Aguzzi, Adriano, Klein, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268467/
https://ncbi.nlm.nih.gov/pubmed/18199638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02036-07
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