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Chronic Subclinical Prion Disease Induced by Low-Dose Inoculum

We have compared the transmission characteristics of the two mouse-adapted scrapie isolates, ME7 and Rocky Mountain Laboratory (RML), in tga20 mice. These mice express elevated levels of PrP protein compared to wild-type mice and display a relatively short disease incubation period following intrace...

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Detalhes bibliográficos
Main Authors: Thackray, Alana M., Klein, Michael A., Aguzzi, Adriano, Bujdoso, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153817/
https://ncbi.nlm.nih.gov/pubmed/11836429
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