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Altering the Intracellular Environment Increases the Frequency of Tandem Repeat Deletion during Moloney Murine Leukemia Virus Reverse Transcription

During retroviral DNA synthesis reverse transcriptase frequently performs nonrequired template switches that can lead to genetic rearrangements or recombination. It has been postulated that template switching occurs after pauses in the action of reverse transcriptase. Hence factors which affect paus...

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Bibliografiske detaljer
Main Authors: Pfeiffer, Julie K., Topping, Robert S., Shin, Nam-Hee, Telesnitsky, Alice
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112863/
https://ncbi.nlm.nih.gov/pubmed/10482596
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