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Altering the Intracellular Environment Increases the Frequency of Tandem Repeat Deletion during Moloney Murine Leukemia Virus Reverse Transcription

During retroviral DNA synthesis reverse transcriptase frequently performs nonrequired template switches that can lead to genetic rearrangements or recombination. It has been postulated that template switching occurs after pauses in the action of reverse transcriptase. Hence factors which affect paus...

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Detalhes bibliográficos
Main Authors: Pfeiffer, Julie K., Topping, Robert S., Shin, Nam-Hee, Telesnitsky, Alice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112863/
https://ncbi.nlm.nih.gov/pubmed/10482596
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