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Altering the Intracellular Environment Increases the Frequency of Tandem Repeat Deletion during Moloney Murine Leukemia Virus Reverse Transcription

During retroviral DNA synthesis reverse transcriptase frequently performs nonrequired template switches that can lead to genetic rearrangements or recombination. It has been postulated that template switching occurs after pauses in the action of reverse transcriptase. Hence factors which affect paus...

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Main Authors: Pfeiffer, Julie K., Topping, Robert S., Shin, Nam-Hee, Telesnitsky, Alice
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112863/
https://ncbi.nlm.nih.gov/pubmed/10482596
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