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Selection of Optimal Polypurine Tract Region Sequences during Moloney Murine Leukemia Virus Replication

Retrovirus plus-strand synthesis is primed by a cleavage remnant of the polypurine tract (PPT) region of viral RNA. In this study, we tested replication properties for Moloney murine leukemia viruses with targeted mutations in the PPT and in conserved sequences upstream, as well as for pools of muta...

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Détails bibliographiques
Auteurs principaux: Robson, Nicole D., Telesnitsky, Alice
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC110903/
https://ncbi.nlm.nih.gov/pubmed/11044073
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