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Selection of Optimal Polypurine Tract Region Sequences during Moloney Murine Leukemia Virus Replication

Retrovirus plus-strand synthesis is primed by a cleavage remnant of the polypurine tract (PPT) region of viral RNA. In this study, we tested replication properties for Moloney murine leukemia viruses with targeted mutations in the PPT and in conserved sequences upstream, as well as for pools of muta...

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Bibliografiske detaljer
Main Authors: Robson, Nicole D., Telesnitsky, Alice
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110903/
https://ncbi.nlm.nih.gov/pubmed/11044073
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