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Selection of Optimal Polypurine Tract Region Sequences during Moloney Murine Leukemia Virus Replication

Retrovirus plus-strand synthesis is primed by a cleavage remnant of the polypurine tract (PPT) region of viral RNA. In this study, we tested replication properties for Moloney murine leukemia viruses with targeted mutations in the PPT and in conserved sequences upstream, as well as for pools of muta...

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Detalhes bibliográficos
Main Authors: Robson, Nicole D., Telesnitsky, Alice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110903/
https://ncbi.nlm.nih.gov/pubmed/11044073
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