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Effects of 3′ Untranslated Region Mutations on Plus-Strand Priming during Moloney Murine Leukemia Virus Replication

A conserved purine-rich motif located near the 3′ end of retroviral genomes is involved in the initiation of plus-strand DNA synthesis. We mutated sequences both within and flanking the Moloney murine leukemia virus polypurine tract (PPT) and determined the effects of these alterations on viral DNA...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Robson, Nicole D., Telesnitsky, Alice
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.948-957.1999
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