A Recombinant Human Cytomegalovirus with a Large Deletion in UL97 Has a Severe Replication Deficiency

Human cytomegalovirus encodes a protein kinase (UL97) that confers sensitivity to ganciclovir by phosphorylating it to the monophosphate. The function of this unusual kinase in viral replication is unknown. We constructed two independent isolates of a recombinant virus, RCΔ97, that contain large del...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Prichard, Mark N., Gao, Ning, Jairath, Sanju, Mulamba, Gilbert, Krosky, Paula, Coen, Donald M., Parker, Breck O., Pari, Gregory S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5663-5670.1999
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