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The Human Cytomegalovirus UL97 Protein Kinase, an Antiviral Drug Target, Is Required at the Stage of Nuclear Egress

Human cytomegalovirus encodes an unusual protein kinase, UL97, that activates the established antiviral drug ganciclovir and is specifically inhibited by a new antiviral drug, maribavir. We used maribavir and a UL97 null mutant, which is severely deficient in viral replication, to determine what sta...

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Detalhes bibliográficos
Main Authors: Krosky, Paula M., Baek, Moon-Chang, Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140798/
https://ncbi.nlm.nih.gov/pubmed/12502806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.905-914.2003
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