The Human Cytomegalovirus UL97 Protein Kinase, an Antiviral Drug Target, Is Required at the Stage of Nuclear Egress

Human cytomegalovirus encodes an unusual protein kinase, UL97, that activates the established antiviral drug ganciclovir and is specifically inhibited by a new antiviral drug, maribavir. We used maribavir and a UL97 null mutant, which is severely deficient in viral replication, to determine what sta...

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הוצא לאור ב:	J Virol
Principais autores:	Krosky, Paula M., Baek, Moon-Chang, Coen, Donald M.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2003
נושאים:	Structure and Assembly
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502806/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.905-914.2003
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