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The Human Cytomegalovirus UL97 Protein Kinase, an Antiviral Drug Target, Is Required at the Stage of Nuclear Egress

Human cytomegalovirus encodes an unusual protein kinase, UL97, that activates the established antiviral drug ganciclovir and is specifically inhibited by a new antiviral drug, maribavir. We used maribavir and a UL97 null mutant, which is severely deficient in viral replication, to determine what sta...

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Main Authors: Krosky, Paula M., Baek, Moon-Chang, Coen, Donald M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC140798/
https://ncbi.nlm.nih.gov/pubmed/12502806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.905-914.2003
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