Acyclovir Is Phosphorylated by the Human Cytomegalovirus UL97 Protein

Acyclovir (ACV) has shown efficacy in the prophylactic suppression of human cytomegalovirus (HCMV) reactivation in immunocompromised renal transplant patients without the toxicity associated with ganciclovir (GCV). The HCMV UL97 gene product, a protein kinase, is responsible for the phosphorylation...

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Autors principals: Talarico, Christine L., Burnette, Thimysta C., Miller, Wayne H., Smith, Sheila L., Davis, Michelle G., Stanat, Sylvia C., Ng, Teresa I., He, Zuwen, Coen, Donald M., Roizman, Bernard, Biron, Karen K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89395/
https://ncbi.nlm.nih.gov/pubmed/10428917
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