Acyclovir Is Phosphorylated by the Human Cytomegalovirus UL97 Protein

Acyclovir (ACV) has shown efficacy in the prophylactic suppression of human cytomegalovirus (HCMV) reactivation in immunocompromised renal transplant patients without the toxicity associated with ganciclovir (GCV). The HCMV UL97 gene product, a protein kinase, is responsible for the phosphorylation...

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Detalhes bibliográficos
Main Authors: Talarico, Christine L., Burnette, Thimysta C., Miller, Wayne H., Smith, Sheila L., Davis, Michelle G., Stanat, Sylvia C., Ng, Teresa I., He, Zuwen, Coen, Donald M., Roizman, Bernard, Biron, Karen K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89395/
https://ncbi.nlm.nih.gov/pubmed/10428917
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