Acyclovir Is Phosphorylated by the Human Cytomegalovirus UL97 Protein

Acyclovir (ACV) has shown efficacy in the prophylactic suppression of human cytomegalovirus (HCMV) reactivation in immunocompromised renal transplant patients without the toxicity associated with ganciclovir (GCV). The HCMV UL97 gene product, a protein kinase, is responsible for the phosphorylation...

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Hlavní autoři: Talarico, Christine L., Burnette, Thimysta C., Miller, Wayne H., Smith, Sheila L., Davis, Michelle G., Stanat, Sylvia C., Ng, Teresa I., He, Zuwen, Coen, Donald M., Roizman, Bernard, Biron, Karen K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89395/
https://ncbi.nlm.nih.gov/pubmed/10428917
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