A Recombinant Human Cytomegalovirus with a Large Deletion in UL97 Has a Severe Replication Deficiency
Human cytomegalovirus encodes a protein kinase (UL97) that confers sensitivity to ganciclovir by phosphorylating it to the monophosphate. The function of this unusual kinase in viral replication is unknown. We constructed two independent isolates of a recombinant virus, RCΔ97, that contain large del...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5663-5670.1999 |
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