Lysosomotropic Agents and Cysteine Protease Inhibitors Inhibit Scrapie-Associated Prion Protein Accumulation
We report that lysosomotropic agents and cysteine protease inhibitors inhibited protease-resistant prion protein accumulation in scrapie-infected neuroblastoma cells. The inhibition occurred without either apparent effects on normal prion protein biosynthesis or turnover or direct interactions with...
שמור ב:
| הוצא לאור ב: | J Virol |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
2000
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4894-4897.2000 |
| תגים: |
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