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Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice
Herpes simplex virus type 1 (HSV-1) mutants that are attenuated for neurovirulence are being used for the treatment of cancer. We have examined the safety of G207, a multimutated replication-competent HSV-1 vector, in mice. BALB/c mice inoculated intracerebrally or intracerebroventricularly with 10(...
में बचाया:
मुख्य लेखकों: | , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Society for Microbiology
2000
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC111891/ https://ncbi.nlm.nih.gov/pubmed/10729157 |
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