Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice

Herpes simplex virus type 1 (HSV-1) mutants that are attenuated for neurovirulence are being used for the treatment of cancer. We have examined the safety of G207, a multimutated replication-competent HSV-1 vector, in mice. BALB/c mice inoculated intracerebrally or intracerebroventricularly with 10(...

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Detaylı Bibliyografya
Asıl Yazarlar: Sundaresan, Periasamy, Hunter, William D., Martuza, Robert L., Rabkin, Samuel D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC111891/
https://ncbi.nlm.nih.gov/pubmed/10729157
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