Nonrandom Transduction of Recombinant Adeno-Associated Virus Vectors in Mouse Hepatocytes In Vivo: Cell Cycling Does Not Influence Hepatocyte Transduction

Recombinant adeno-associated virus vectors (rAAV) show promise in preclinical trials for the treatment of genetic diseases including hemophilia. Liver-directed gene transfer results in a slow rise in transgene expression, reaching steady-state levels over a period of 5 weeks concomitant with the con...

詳細記述

書誌詳細

出版年:	J Virol
主要な著者:	Miao, Carol H., Nakai, Hiroyuki, Thompson, Arthur R., Storm, Theresa A., Chiu, Winnie, Snyder, Richard O., Kay, Mark A.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2000
主題:	Gene Therapy
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10729154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.8.3793-3803.2000
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