Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis.
Adeno-associated virus is an integrating DNA parvovirus with the potential to be an important vehicle for somatic gene therapy. A potential barrier, however, is the low transduction efficiencies of recombinant adeno-associated virus (rAAV) vectors. We show in this report that adenovirus dramatically...
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| Publicado no: | J Virol |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.520-532.1996 |
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