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Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis.

Adeno-associated virus is an integrating DNA parvovirus with the potential to be an important vehicle for somatic gene therapy. A potential barrier, however, is the low transduction efficiencies of recombinant adeno-associated virus (rAAV) vectors. We show in this report that adenovirus dramatically...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Fisher, K J, Gao, G P, Weitzman, M D, DeMatteo, R, Burda, J F, Wilson, J M
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.520-532.1996
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