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Complete Translation of the Hepatitis C Virus Genome In Vitro: Membranes Play a Critical Role in the Maturation of All Virus Proteins except for NS3

We developed an in vitro translation extract from Krebs-2 cells that translates the entire open reading frame of the hepatitis C virus (HCV) strain H77 and properly processes the viral protein precursors when supplemented with canine microsomal membranes (CMMs). Translation of the C-terminal portion...

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Autori principali: Svitkin, Yuri V., Pause, Arnim, Lopez-Lastra, Marcelo, Perreault, Sandra, Sonenberg, Nahum
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1112104/
https://ncbi.nlm.nih.gov/pubmed/15890926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.11.6868-6881.2005
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