La Autoantigen Is Necessary for Optimal Function of the Poliovirus and Hepatitis C Virus Internal Ribosome Entry Site In Vivo and In Vitro

Translation of poliovirus and hepatitis C virus (HCV) RNAs is initiated by recruitment of 40S ribosomes to an internal ribosome entry site (IRES) in the mRNA 5′ untranslated region. Translation initiation of these RNAs is stimulated by noncanonical initiation factors called IRES trans-activating fac...

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Bibliographic Details
Main Authors: Costa-Mattioli, Mauro, Svitkin, Yuri, Sonenberg, Nahum
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC444852/
https://ncbi.nlm.nih.gov/pubmed/15254251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6861-6870.2004
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