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Functional Characterization of the X-Linked Inhibitor of Apoptosis (XIAP) Internal Ribosome Entry Site Element: Role of La Autoantigen in XIAP Translation

X-linked inhibitor of apoptosis protein (XIAP) is a key regulator of programmed cell death triggered by various apoptotic triggers. Translation of XIAP is controlled by a 162-nucleotide (nt) internal ribosome entry site (IRES) element located in the 5′ untranslated region of XIAP mRNA. XIAP IRES med...

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Библиографические подробности
Главные авторы: Holcik, Martin, Korneluk, Robert G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC85872/
https://ncbi.nlm.nih.gov/pubmed/10848591
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