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An internal ribosomal entry site mediates redox-sensitive translation of Nrf2

Nrf2 plays pivotal roles in coordinating the antioxidant response and maintaining redox homeostasis. Nrf2 expression is exquisitely regulated; Nrf2 expression is suppressed under unstressed conditions but strikingly induced under oxidative stress. Previous studies showed that stress-induced Nrf2 up-...

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Détails bibliographiques
Auteurs principaux: Li, Wenge, Thakor, Nehal, Xu, Eugenia Y., Huang, Ying, Chen, Chi, Yu, Rong, Holcik, Martin, Kong, Ah-Ng
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817467/
https://ncbi.nlm.nih.gov/pubmed/19934254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1048
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