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Tumor Suppressor PDCD4 Represses Internal Ribosome Entry Site-Mediated Translation of Antiapoptotic Proteins and Is Regulated by S6 Kinase 2

Apoptosis can be regulated by extracellular signals that are communicated by peptides such as fibroblast growth factor 2 (FGF-2) that have important roles in tumor cell proliferation. The prosurvival effects of FGF-2 are transduced by the activation of the ribosomal protein S6 kinase 2 (S6K2), which...

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Main Authors: Liwak, Urszula, Thakor, Nehal, Jordan, Lindsay E., Roy, Rajat, Lewis, Stephen M., Pardo, Olivier E., Seckl, Michael, Holcik, Martin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347423/
https://ncbi.nlm.nih.gov/pubmed/22431522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06317-11
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