Reduced Susceptibility of Human Immunodeficiency Virus Type 1 (HIV-1) from Patients with Primary HIV Infection to Nonnucleoside Reverse Transcriptase Inhibitors Is Associated with Variation at Novel Amino Acid Sites

Recently, significant numbers of individuals with primary human immunodeficiency virus (HIV) infection have been found to harbor viral strains with reduced susceptibility to antiretroviral drugs. In one study, HIV from 16% of such antiretroviral-naive individuals was shown to have a susceptibility t...

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Bibliographic Details
Main Authors: Brown, Andrew J. Leigh, Precious, Heather M., Whitcomb, Jeannette M., Wong, Joseph K., Quigg, Marlynne, Huang, Wei, Daar, Eric S., D'Aquila, Richard T., Keiser, Philip H., Connick, Elizabeth, Hellmann, Nicholas S., Petropoulos, Christos J., Richman, Douglas D., Little, Susan J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110900/
https://ncbi.nlm.nih.gov/pubmed/11044070
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