Reduced Susceptibility of Human Immunodeficiency Virus Type 1 (HIV-1) from Patients with Primary HIV Infection to Nonnucleoside Reverse Transcriptase Inhibitors Is Associated with Variation at Novel Amino Acid Sites

Recently, significant numbers of individuals with primary human immunodeficiency virus (HIV) infection have been found to harbor viral strains with reduced susceptibility to antiretroviral drugs. In one study, HIV from 16% of such antiretroviral-naive individuals was shown to have a susceptibility t...

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Detalhes bibliográficos
Main Authors: Brown, Andrew J. Leigh, Precious, Heather M., Whitcomb, Jeannette M., Wong, Joseph K., Quigg, Marlynne, Huang, Wei, Daar, Eric S., D'Aquila, Richard T., Keiser, Philip H., Connick, Elizabeth, Hellmann, Nicholas S., Petropoulos, Christos J., Richman, Douglas D., Little, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110900/
https://ncbi.nlm.nih.gov/pubmed/11044070
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